副教授
E-mail:yangjing2018@nwu.edu.cn
主要研究领域
水凝胶类生物医用材料
基因递送促进生物支架材料的内皮化
天然活性产物生物合成、封装及递送
教育背景
2016.09-2018.01德国柏林自由大学化学与生物化学博士后
2015.09-2015.10德国亥姆霍兹研究所生物材料交换生
2013.09-2016.06天津大学应用化学工学博士
主持科研项目
1.国家重点研发计划（2021YFC2101500）：天然活性产物生物制造技术（课题名称2“天然产物生物合成细胞工厂适配原理解析与关键技术”子课题负责人），2021.07-2024. 06；
2.国家自然科学基金青年项目（22108225）：自收缩microRNA21高转染促伤口愈合多功能水凝胶的构建及机制研究，2022.01-2024.12;
3.陕西省自然科学基金项目（2021JQ-434）：促收缩可注射水凝胶敷料的制备及应用，2021.01-2022.12.12；
4.中国博后科学基金（2018M643720）：人参皂苷Rh4抑制原位结肠癌生长及转移的机制研究，2018.12-2020.08。
研究成果
1. Sprayable nanodrug-loaded hydrogels with enzyme-catalyzed semiinter penetrating polymer network (Semi-IPN) for solar dermatitis. Jialing Yao, Junfeng Hui, Jing Yang, Jiaxin Yao, Chaoquan Hu, Daidi Fan. Nano Research. 2022, https://doi.org/10.1007/s12274-022-4236-3.
2. An ultrasmall infinite coordination polymer nanomedicine-composited biomimetic hydrogel for programmed dressing-chemo-low level laser combination therapy of burn wounds. Shihong Shen, Daidi Fan, Yang Yuan, Xiaoxuan Ma, Jing Zhao, Jing Yang. Chemical Engineering Journal. 2021, 426: 130610.
3. Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma. Manling Hu, Jing Yang,Linlin Qu, Xuqian Deng, Zhiguang Duan, Rongzhan Fu, Lihua Liang, Daidi Fan. Food & Function. 2020, 11 (1): 456-471.
4. Eurocristatine, a plant alkaloid from Eurotiumcristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway Author links open overlay panel. HuiZhang, JunfengHui, JingYang, JianjunDeng, DaidiFan. European Journal of Pharmacology. 2020, 887, 173557.
5. Folic acid-modified ginsenoside Rg5-loaded bovine serum albumin nanoparticles for targeted cancer therapy in vitro and in vivo. Yanan Dong, Rongzhan Fu, Jing Yang, Pei Ma, Lihua Liang, Yu Mi, Daidi Fan. International Journal of Nanomedicine. 2019, 14: 6971-6988.
6.Jing Yang, Xuefang Hao, Qian Li, Mary Akpanyung, AbdelilahNejjari, Agnaldo Luis Neve, Xiangkui Ren, Jintang Guo, Yakai Feng, Changcan Shi, Wencheng Zhang. CAGW Peptide and PEG Modified Gene Carrier for Selective Gene Delivery and Promotion on Angiogenesis of HUVECs In Vivo. ACS Applied Materials & Interfaces. 2017.
7. Jing Yang, Wen Liu, Juan Lv, Yakai Feng, Xiangkui Ren, Wencheng Zhang. REDV-polyethyleneimine complexes for selectively enhancing gene delivery in endothelial cells. Journal of Materials Chemistry B. 2016.
8. Jing Yang, Musammir Khan, Li Zhang, Xiangkui Ren, Jintang Guo, Yakai Feng, Shuping Wei, Wencheng Zhang. Antimicrobial surfaces grafted random copolymers with REDV peptide beneficial for endothelialization. Journal of Materials Chemistry B. 2015.
9. Jing Yang, Qian Li, Xiao Yang, Yakai Feng, Xiangkui Ren, Changcan Shi, Wencheng Zhang. Multitargeting gene delivery systems for enhancing the transfection of endothelial cells. Macromolecular Rapid Communications. 2016.
10. Jing Yang, Juan Lv, Marc Behl, Andreas Lendlein, Dazhi Yang, Li Zhang, Changcan Shi, Jintang Guo, Yakai Feng. Functionalization of polycarbonate surfaces by grafting PEG and zwitterionic polymers with a multicomb structure. Macromolecular Bioscience. 2013.
11. Jing Yang, Yakai Feng, Li Zhang. Biodegradable Carrier/Gene Complexes to Mediate the Transfection and Proliferation of Human Vascular Endothelial Cells. Polymers for Advanced Technologies. 2015.
12. Jing Yang, Juan Lv, Bin Gao, Li Zhang, Dazhi Yang, Changcan Shi, Jintang Guo, Wenzhong Li, Yakai Feng. Modification of polycarbonateurethane surface with poly(ethylene glycol) monoacrylate and phosphorylcholine glyceraldehyde for anti-platelet adhesion. Frontiers of chemical science and engineering. 2014.
13.Xiangkui Ren, Yakai Feng, Jintang Guo, Haixia Wang, Qian Li, Jing Yang, Xuefang Hao, Juan Lv, Nan Ma, Wenzhong Li. Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications. Chemical Society Review. 2015.
