主要研究领域

主要从事小分子靶向药物的设计与合成；候选药物的体内外药效学、成药性评价及作用靶点鉴定；以及通过设计新型配体分子，探索目标蛋白的生物学功能。

教育经历

1. 博士，生物与医药专业，四川大学， 2017.09 -2020.06；

2. 硕士，制药工程专业，四川大学，2012.09-2015.06；

3. 学士，制药工程专业，四川大学，2008.09 -2012.06。

学术机构任职

1.陕西省干细胞学会会员；

2.中国药学会会员；

3.中国化学会会员。

代表性论文（限5篇）

1. Shuguang Yang,  Yanxin Zhang, Xiaoping Song, Qingchao Liu*, Daidi Fan*, Ying Xu*. Progress of structurally diverse cereblon (CRBN) ligands and their application in PROTAC degraders. Bioorganic Chemistry, 2026, 178, 109968.

2. Zhihao Liu#, Ying Xu#, Wei Wei#, Zuli Hu, Jiuyu Gao, Tianqiong Yang, Longyue Tao, Hualong He, Xingping Su, Lin Yue, Shuyan Zhou, Tinghong Ye, Ningyu Wang*, Luoting Yu*. Discovery of a Potent FLT3 Inhibitor (E)-4-(3-(3-Fluoro-4-(morpholinomethyl) styryl)-1H-indazol-6-yl) pyridin-2-amine for the Treatment of Acute Myeloid Leukemia with Multiple FLT3 Mutations. Journal of Medicinal Chemistry, 2025, 68 (11), 11894-11915.

3. Ying Xu#; Qianqian Wang#; Kunjie Xiao; Zhihao Liu; Lifeng Zhao; Xuejiao Song; Xi Hu; Zhanzhan Feng; Tiantao Gao; Weiqiong Zuo; Jun Zeng; Ningyu Wang*; Luoting Yu*; Novel dual BET and PLK1 inhibitor WNY0824 exerts potent anti-tumor effects in CRPC by inhibiting transcription factor function and inducing mitotic abnormality, Molecular Cancer Therapeutics, 2020, 19(6), 1221-1231.

4. Ning-Yu Wang#; Ying Xu#; Kun-Jie Xiao; Wei-Qiong Zuo; Yong-Xia Zhu; Rong Hu; Wan-Li Wang; Yao-Jie Shi; Luo-Ting Yu*; Zhi-Hao Liu*; Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4] triazolo[4,3-f] pteridine derivatives as novel dual-PLK1/BRD4 inhibitors, European Journal of Medicinal Chemistry, 2020, 191, 112152.

5. Ning-Yu Wang#; Ying Xu#; Wei-Qiong Zuo; Kun-Jie Xiao; Li Liu; Xiu-Xiu Zeng; Xin-Yu You; Li-Dan Zhang; Chao Gao; Zhi-Hao Liu; Ting-Hong Ye; Yong Xia; Ying Xiong; Xue-Jiao Song; Qian Lei; Cui-Ting Peng; Hong Tang; Sheng-Yong Yang; Yu-Quan Wei; Luo-Ting Yu*; Discovery of Imidazo[2,1-b]thiazole HCV NS4B Inhibitors Exhibiting Synergistic Effect with Other Direct-Acting Antiviral Agents, Journal of Medicinal Chemistry, 2015, 58(6), 2764-2778.